Adherence to Bisphosphonate Therapy and Fracture Rates in Osteoporotic Women Relationship to Vertebral and Nonvertebral Fractures From 2 US Claims Databases

ETHEL S. SIRIS, MD; STEVEN T. HARRIS, MD; CLIFFORD J. ROSEN, MD; CHARLES E. BARR, MD, MPH;

JAMES N. ARVESEN, PHD; THOMAS A. ABBOTT, PHD, MBA; AND STUART SILVERMAN, MD

OBJECTIVE: To characterize the relationships between adherence (compliance and persistence) to bisphosphonate therapy and risk of specific fracture types in postmenopausal women.